Ongoing projects and patient cohorts
Mucosal measurements to target Mucosal therapies:
Use respiratory samples as biosensor
We use respiratory samples as biosensors, offering real-time insights into the mucosal immune response, to improve clinical decision-making in paediatric respiratory infections.
Analyzing proteins, pathogens, and immune cells in these samples unveils the dynamic interplay between host defenses and pathogens. Moreover, respiratory sampling (e.g. saliva collection) is child-friendly, unlike blood draws.
Our goal is to integrate respiratory sampling into routine practice, enhancing diagnostics and tailoring treatment for individual patients, thereby optimizing clinical care.
Identify mucosal immune-based therapies
We explore the respiratory mucosa’s immunological landscape in children to discover innovative immune-based therapies for paediatric respiratory tract infections.
These therapies aim to enhance local immune defence against respiratory pathogens.
Through a combination of preclinical studies, translational research and clinical studies including patients we strive to develop targeted interventions that improve respiratory tract infection outcomes for vulnerable children worldwide.
